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KMID : 0356420020200030153
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Journal of Korean Andrology
2002 Volume.20 No. 3 p.153 ~ p.156
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Double-Blind Study of Intrarectal Administration of Anesthetic Agent for Pain Control during Transrectal Prostatic Biopsy
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Park Im-Chan
Jeong Young-Beom
Park Young-Kyung
Park Jong-Kwan
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Abstract
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Purpose: We evaluated the safety and efficacy of intrarectal administration of anesthetic agent for transrectal prostate biopsy.
Materials and Methods: For a double-blind prospective trial, 100 men undergoing transrectal prostate biopsy were randomized into three groups using an established list. In the control group(n=36), 40mL of normal saline was administered transrectally 10 min before the procedure. The lidocaine group(n=31) and the benzocaine group(n=33) were give 40 mL of 1% lidocaine and 0.3% benzocaine, respectively. Patients were asked to score the severity of the pain expected before and after the biopsy procedure using a self-administered verbal rating scale. Pain was assessed using a 10-point linear visual analog scale.
Results: The median pain score expected before the transrectal prostate biopsy was 6.7+-0.3, 7.1+-0.2, and 6.7+-0.3 in the control, lidocaine, and benzocaine group, respectively. The median pain score during the biopsy was 6.1+-0.3, 5.8+-0.3(P＜0.05), and 5.9+-0.4 in the control, lidocaine, and benzocaine group, respectively. Ninety seven percent of the control group, 100% of the lidocaine group, and 91% of the benzocaine group complained of severe and bothersome pain, with a score of 5 or greater during the biopsy. No adverse events were noted.
Conclusions: Intrarectal administration of anesthetic agent is a simple, safe, and efficacious method of providing satisfactory anesthesia in patients undergoing transrectal prostate biopsy. We recommend 1% lidocaine solution in the patients to perform transrectal prostatic biopsy.
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KEYWORD
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Anesthetic agents, Prostate biopsy, Lidocaine, Benzocaine
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